DEPOT MEDROXYPROGESTERONE ACETATE (DMPA) ENHANCES SUSCEPTIBILITY AND INCREASES THE WINDOW OF VULNERABILITY TO HIV-1 IN HUMANIZED MICE

Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

Abstract The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic.Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (HIV-1).Therefore understanding how DMPA inc

read more


Measurement of some body parts of muscovy duck (Carina moschata) at age 3 weeks old fed by pellet feed under an intensive farming system

This study was aimed to measure and determine the size redken 07m of some body parts of the muscovy duck (Carina moschata) and their relationship with body weight.The research was be carried out for two months from August to September 2023 in local Intensive Muscovy Duck farm, Kademangan area, Blitar, East Java.The research material use were 60 mus

read more

7-hydroxy-3-(1-hydroxyethyl)-5-methoxy-3-4-dimethylisobenzofuran-a(3H)-one and 4, 8-dihydroxy-6-methoxy-3,4,5-trimethyIisochroman-1-one using MOPAC Software

A benzofuranone type of compound known as 7-hydroxy-3-(1-hydroxyethyl)-5methoxy-3,4-dimethylisobenzofuran-1 (3H)-one (1) and 4,8-dihydroxy-6-methoxy-3,4,5trimethylisochroman-l-one (2) were studied for the molecular modeling using MOPAC.Compound 1 was originally isolated from the fungus Leptosphaeria sp.KTC 727.Initial Nuclear Magnetic Resonance (NM

read more